Infection of Man with Mimeae

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Abstract
Within a 14-month-period at Johns Hopkins Hospital 77 cultures of Mimeae organisms were isolated from human tissues and excretions. In 42 individuals these bacteria were specifically responsible for many types of infection ranging from impetigo to near fatal septicemia. Infection was most common in respiratory or urinary tracts and occurred more frequently among the very young and very old. Mimeae are almost uniformly sensitive to most broad spectrum antibiotics except chloramphenicol, and are resistant to penicillin. Unless laboratory personnel and clinicians are aware of the existance of these bacteria and their human patho-genicity, they are seldom recognized as a significant cause of human infection. A simple bacteriological scheme is described in order to facilitate their recognition in the laboratory. The clinical material comprising 44 cases of human infection is analyzed and several case histories recorded to emphasize the role of these obscure Gram negative organisms as human pathogens.
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