Cortical calcium waves in resting newborn mice
- 10 July 2005
- journal article
- research article
- Published by Springer Nature in Nature Neuroscience
- Vol. 8 (8) , 988-990
- https://doi.org/10.1038/nn1502
Abstract
Using a new optical fiber–based approach, we demonstrate the presence of recurrent Ca2+ transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca2+ waves reflect the correlated activity of thousands of cells and were detected only in resting, but not in moving pups. Our results suggest that Ca2+-dependent cortical maturation occurs predominantly during the intermittent sleep-like resting periods that are characteristic for the first days of postnatal life.Keywords
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