Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine
- 1 November 1983
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 46 (6) , 852-861
- https://doi.org/10.1021/np50030a005
Abstract
Attempts to isolate the putative endogenous ligand for the benzodiazepine receptor from bovine urine resulted in the identification of 3 isoflavans: equol (1), 3'',7-dihydroxyisoflavan (2) and 4''-hydroxy-7-methoxyisoflavan (9), as diazepam-like compounds. 3-Chloro-9H-carbazole (17) enhanced the binding of diazepam in the benzodiazepine receptor binding assay. Pinosylvine monomethyl ether (18), indigo (20) and indirubin (21) were isolated as inactive compounds.This publication has 4 references indexed in Scilit:
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