TWO CASES OF LYMPHOMA OF THE PAROTID GLAND FOLLOWING ABLATIVE RADIOIODINE THERAPY FOR THYROID CARCINOMA

Abstract
Two adult patients are described in whom 131I therapy for thyroid carcinoma was followed by the development of non-Hodgkin''s lymphoma in salivary glands. Histologically one was lymphocytic and the other histiocytic. The total doses of 131I given were 27 GBq (675 mCi) and 14 GBq (350 mCi), lymphoma presenting 10 and 3 yr, respectively, after the initial therapeutic dose of 131I. The relationship apparently is a causal one, because of the rarity of salivary gland lymphoma, and the high dose of radiation to the salivary glands with this mode of therapy.