EPIDEMIOLOGIC AND CLINICAL OBSERVATIONS IN SARCOIDOSIS

Abstract
The geographic concentration of 1700 male veteran patients with sarcoidosis was found predominately in Eastern United States. Counties and communities with high prevalence rates when corrected for population and race are located in the "pine belt" and often have lumbering as a principal industry. A 5-year follow-up of 540 of these patients revealed that cor pulmonale and tuberculosis were frequent causes of death. A review of autopsy findings suggests that tuberculosis, carcinoma and Hodgkin''s disease may produce sarcoid gran-ulomata or may be confused with the clinical diagnosis of sarcoidosis. No unequivocal evidence of the course of this disease or syndrome is yet available although pine pollen has been suggested as a possible inciting agent.
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