Linoleic Acid Hydroperoxide: Impaired Bacterial Uptake by Alveolar Macrophages, a Mechanism of Oxidant Lung Injury
- 28 December 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 182 (4119) , 1364-1365
- https://doi.org/10.1126/science.182.4119.1364
Abstract
Exogenous linoleic acid hydroperoxide causes in vitro impairment of both bacterial uptake and the phagocytic stimulation of (14)CO(2) production from [1-(14)C]glucose in rabbit alveolar macrophages by an undefined effect on the cell membrane. This effect may be one mechanism for the defective pulmonary bacterial clearance characteristic of oxidant lung injury.Keywords
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