Vascular endothelial growth factor in esophageal cancer
- 23 July 2004
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 87 (2) , 95-104
- https://doi.org/10.1002/jso.20070
Abstract
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis of many solid malignancies. The influence of angiogenesis and VEGF expression on progression and recurrence of esophageal cancer has been investigated over the last years. This article reviews the prognostic significance of VEGF expression, microvessel density (MVD), and lymphangiogenic factors in squamous cell carcinoma (SCC), Barrett's dysplasia, and adenocarcinoma (AC) of the esophagus, their predictive value for treatment response to chemo‐radiotherapy and new anti‐angiogenic treatment strategies. J. Surg. Oncol. 2004;87:95–104.Keywords
This publication has 71 references indexed in Scilit:
- Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cellsPublished by Elsevier ,2004
- Ets-1 and VEGF expression correlates with tumor angiogenesis, lymph node metastasis, and patient survival in esophageal squamous cell carcinomaZeitschrift für Krebsforschung und Klinische Onkologie, 2003
- Effect of multimodality therapy on ciculating vascular endothelial growth factor levels in patients with oesophageal cancer (Br J Surg 2001; 88: 1105–9)British Journal of Surgery, 2002
- Effect of multimodality therapy on circulating vascular endothelial growth factor levels in patients with oesophageal cancerBritish Journal of Surgery, 2001
- Esophageal cancer: results of an American College of Surgeons patient care evaluation studyJournal of the American College of Surgeons, 2000
- Vascular endothelial growth factorEuropean Journal Of Cancer, 1996
- Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppressionNature Medicine, 1995
- Angiogenic effects of macrophages isolated from ascitic fluid aspirated from women with advanced ovarian cancerCancer Letters, 1992
- Histopathological evaluation of oesophageal carcinoma: The significance of venous invasionBritish Journal of Surgery, 1991
- Induction of angiogenesis during the transition from hyperplasia to neoplasiaNature, 1989