XV. Contributions to animal chemistry. —Paper V. On the oxidation of ammonia in the human body, with some remarks on nitrification

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Abstract
In a paper lately communicated to the Royal Society, I showed that the effect of tartrate of ammonia on the acidity of the urine was totally different from that of tartrate of potash; and that carbonate of ammonia taken in very large quantities did not produce any alkaline reaction of the urine; on the contrary, the acidity was rather increased than diminished by large doses of carbonate of ammonia. I repeated these experiments with carbonate of ammonia, hoping to obtain more decided results; but I could not determine the fact of any great increase in the acidity of the urine, although it was again apparent that no diminution of the acid reaction resulted from taking carbonate of ammonia. I also repeated these experiments on many patients in St. George’s Hospital suffering from chronic rheumatism, but though some took on an average 50 grs. of carbonate of ammonia daily for seven or more weeks, yet no alkaline state of the urine could be produced.
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