Nucleotide sequences of normal and rearranged RNA segments 10 of human rotaviruses
- 1 March 1992
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 73 (3) , 633-638
- https://doi.org/10.1099/0022-1317-73-3-633
Abstract
Normal and rearranged RNA segments 10 of group A rotaviruses isolated from a chronically infected immunodeficient child were amplified by the polymerase chain reaction as full-length cDNA copies, and were subsequently cloned and sequenced. Compared with the nucleotide sequence of the normal RNA segment 10, the rearranged form contains a partial non-coding duplication at its 3′ end and several point mutations. The normal RNA segment 10 was similar to that of bovine rotavirus.Keywords
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