Immobilization and Characterization of L-Asparaginase on Hollow Fibers
- 1 March 1980
- journal article
- research article
- Published by SAGE Publications in The International Journal of Artificial Organs
- Vol. 3 (2) , 120-123
- https://doi.org/10.1177/039139888000300214
Abstract
L-Asparaginase was immobilized with various methods: cyanogen bromide, cyanuric chloride and cross-linking with glutaraldehyde. A dialysis device was transformed in a bioreactor with the enzyme immobilized on the outer surface of hollow fibers. Results on kinetic behavior, stability in storage and lyophilization are reported.Keywords
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