Treatment of Bone-Marrow Failure by Isogeneic Marrow Infusion

14 July 1966

journal article
case report
Published by Massachusetts Medical Society in New England Journal of Medicine

Vol. 275 (2) , 94-97
https://doi.org/10.1056/nejm196607142750209

Abstract

BONE-marrow failure, or "aplastic anemia," whether idiopathic or induced by drugs, is an illness of obscure pathophysiology and high mortality.¹ Treatment of this illness by infusion of normal marrow cells from an identical twin is of particular interest since growth of the infused marrow suggests the absence of "toxins" and the presence of normal nutrient factors.² This report describes another case of successful treatment of acute bone-marrow failure by isogeneic marrow infusion and reviews the experiences in 9 similar cases.Case ReportAn 18-year-old boy, previously in excellent health, began to complain of a sore throat about September 12, 1964. . . .

Keywords

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Recovery From Marrow Failure Following Isogenic Marrow Infusion
Published by American Medical Association (AMA) ,1964
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