Convulsions Associated with High Cumulative Doses of Metronidazole
- 1 May 1982
- journal article
- case report
- Published by SAGE Publications in Drug Intelligence & Clinical Pharmacy
- Vol. 16 (5) , 409
- https://doi.org/10.1177/106002808201600511
Abstract
Metronidazole in high cumulative doses has been associated with convulsions. A case is presented in which this relationship is clear. In all reported cases of metronidazole-associated seizures, the cumulative dose of metronidazole has been high (> 40 g). The cumulative dose rather than the serum level is important in the pathogenesis of this complication.Keywords
This publication has 6 references indexed in Scilit:
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- Neurologic Toxicity Associated with High-Dose Metronidazole TherapyAnnals of Internal Medicine, 1978
- Metronidazol-Encephalopathie der RatteActa Neuropathologica, 1973