Elevation of glutamic pyruvic transaminase and .GAMMA.-glutamyl transpeptidase in obesity.

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Abstract
Glutamic pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT) and .gamma.-glutamyl transpeptidase (.gamma.-GTP) were studied in 729 obese subjects in various groups, i.e., primary school children, high school children, university students and outpatients. The incidences of abnormal GPT, GOT and .gamma.-GTP in the obese subjects were frequently significantly higher than in the controls and most clearly shown in GPT. The incidence of abnormal GPT in the obese females was significantly lower in the obese males, but was significantly higher than in the controls. Higher incidence of abnormality in the school children was ascribed to the higher degree of obesity in the children. The extent of increase in GPT was considerable. GPT was sometimes higher than 6 times the normal upper limit.

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