Structure and Syntheses of SEN-125 and Oxotomaymycin

Abstract
The structure of SEN-215 was determined as (11aS) (E)-2-ethylidene-2,3,5,10,11,11a-hexahydro-8-hydroxy-7-methoxy-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine by conversion of (E)- and (Z)-pretomaymycin into (E)- and (Z)-SEN-215.
Keywords

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