Analogues of diaminopimelic acid as inhibitors of bacterial growth
- 1 December 1954
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 58 (4) , 520-523
- https://doi.org/10.1042/bj0580520
Abstract
The synthesis of six alpha, alpha[image]-diaminodicarboxylic acids, homologues of alpha, alpha[image]-diaminopimelic acid is described. These were tested as growth inhibitors against Corynebacterium diphtheriae. Staphylococcus aureus. Escherichia coli. and Streptococcus pyogenes. alpha, alpha[image] -Diaminosuberic acid alone gave significant growth inhibition and this agent failed to give any protection to mice against S. pyogenes.Keywords
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