Granulocyte Transfusions: Where Now?

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Abstract
Although the article on prophylactic granulocyte transfusions in acute myelogenous leukemia by Strauss et al. in this issue of the Journal1 might be criticized — for the low number of granulocytes given per transfusion, for the inclusion of patients with fever, or for the probable differences in antimicrobial-therapy practice and remission-induction regimens among the participating institutions — it describes a carefully done study, with conclusions well supported by the data. These workers found no evidence of benefit and concluded that routine prophylactic transfusions of white cells are not justified.Although many investigators have come to believe that prophylactic granulocyte transfusions . . .