C-2 Epimerization ofN-Acetylglucosamine in an Oligosaccharide Derived From Heparan Sulfate
- 1 April 1996
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 15 (3) , 351-360
- https://doi.org/10.1080/07328309608005658
Abstract
The isolation of a heparan sulfate derived tetrasaccharide containing N-acetylmannosamine is described. The N-acetylmannosamine residue at the reducing terminus of heparin lyase derived tetrasaccharide is formed by base catalyzed C-2 epimerization of N-acetylglucosamine. This C-2 epimerization takes place under very mild conditions suggesting that this residue may be formed in small amounts under physiologic conditions.Keywords
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