Window of Detection of γ-Hydroxybutyrate in Blood and Saliva

Abstract
γ-Hydroxybutyrate (GHB) is an endogenous constituent of the brain, produced by the metabolism of γ-aminobutyric acid and believed to play a role in neurotransmission (1). GHB is a suppressant of the central nervous system that is used in some countries as an anesthetic adjunct and is also sometimes used in treating sleep disorders and alcoholism (2). The primary effects of GHB are those of a depressant and can include reducing inhibition, increasing libido, and causing amnesia, seizure, unconsciousness, coma, and death.

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