SARCOIDOSIS WITH LARGE NODULAR LESIONS SIMULATING PULMONARY METASTASES - ANALYSIS OF 126 CASES OF INTRATHORACIC SARCOIDOSIS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 58  (1) , 11-16
Abstract
Multiple, large, metastasis-like, nodular lesions (LNL) are a rare manifestation of acute/subacute pulmonary sarcoidosis. It was previously only described in American series and all patients but one were Negroes. To estimate the frequency of LNL in a Danish series, 126 consecutive patients with intrathoracic sarcoidosis were examined with regular follow-up for 1/2-5 1/5 yr. LNL simulating pulmonary metastases was found in 2 cases, a frequency corresponding to the American figures. In both cases pulmonary infiltrations disappeared within 3/4 and 1 1/4 yr, respectively. In 1 case, a normal chest roentgenogram was obtained 6 wk before the onset of LNL. The importance of biopsy is emphasized. Sarcoidosis with LNL appears to have a favorable prognosis in many cases.

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