A 33 year old man ingested approximately 3000 mg of verapamil in attempted suicide. Verapamil and norverapamil concentrations 4.5 h after ingestion were 1250 and 1350 ng/ml. The patient had a heart rate of 79 beats/min, a systolic blood pressure of 60 mm Hg and atrioventricular dissociation. Metaraminol had no significant effect on blood pressure or heart rate. During infusion of 10 ml 10% calcium gluconate, systolic blood pressure rose to 80 mm Hg and both QRS and P waves changed polarity. The clinical condition improved and sinus rhythm was established 5 h later. Calcium can be recommended as the first line of treatment in verapamil intoxication.