Abstract
Homogenates of irradiated and non-irradiated skin from 16 patients with chronic polymorphous light eruptions (CPLE) were examined to detect possible light-induced antigen to cell-mediated immunity. The leukocyte migration agarose tests which were performed disclosed no evidence of migration inhibition in either type of skin. These findings do not support the theory of CPLE being a delayed hypersensitivity reaction against an antigen formed in the skin by actinic radiation.

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