Cycloaddition of a nitrone to 2-aminobut-3-en-1-ol for large-scale preparation of 3-aminopiperidin-4-ols: a new asymmetric synthesis of (2R, 4R, 5S)-tetrahydropseudodistomin
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 773-775
- https://doi.org/10.1039/p19940000773
Abstract
Cycloaddition of the nitrone, derived from tetradecanal, to 2-aminobut-3-en-1-ol provides a practical asymmetric synthesis of both (2R,4R,5S)-tetrahydropseudodistomin and all the stereoisomers of racemic tetrahydropseudodistomin.Keywords
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