FORMATION OF BACITRACIN BY WASHED CELL SUSPENSIONS OF BACILLUS LICHENIFORMIS
- 1 October 1960
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 80 (4) , 552-557
- https://doi.org/10.1128/jb.80.4.552-557.1960
Abstract
The biosynthesis of Bacitracin was shown to involve the incorporation of radioactive phenylalanine, leucine, aspartic acid, glutamic acid, onithine, lysine, and histidine. The amount of incorporation of the labelled amino acids into Bacitracin, which was isolated by column chromatography, corresponds to the amount of microbiologically determined antibiotic formed. The formation of the antibiotic is stimulated by additions of glucose, isoleucine, cysteine and an unidentified factor derived from soybean protein.This publication has 6 references indexed in Scilit:
- Cellulose Ion Exchange and Rotatory Dispersion Studies with the Bacitracin PolypeptidesJournal of the American Chemical Society, 1959
- Experiments on the lysine and aspartic acid residues in bacitracin ABiochemical Journal, 1956
- The N-terminal and sulphur-containing residues of bacitracin ABiochemical Journal, 1955
- On the Partial Hydrolysis of DNP-Bacitracin AJournal of the American Chemical Society, 1955
- Partial Hydrolysis Studies with Bacitracin AJournal of the American Chemical Society, 1955
- The assay of bacitracinJournal of the American Pharmaceutical Association (Scientific ed.), 1948