Two new metabolites from the mangrove endophytic fungus No. 2524
- 1 September 2004
- journal article
- research article
- Published by Taylor & Francis in Journal of Asian Natural Products Research
- Vol. 6 (3) , 185-191
- https://doi.org/10.1080/102860201653237
Abstract
Two new metabolites, the cyclo-(l-Phe-l-Leu1-l-Leu2-l-Leu3-l-Ile) (1) and (3S,4R)-dihydroxy-(6S)-undecyl-α-pyranone (2) have been produced by the endophytic fungus no. 2524 isolated from a seed of mangrove Avicennia marina in Hong Kong. The structures have been elucidated by spectra including two-dimensional NMR, ESI tandem mass spectrometry and CD. These compounds show no activity toward human cancer cell lines Bel-7402, NCI-4460 and the normal human cell lines L-02.Keywords
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