Central interaction between the baroreceptor reflexes from the carotid sinus and aortic arch
- 1 January 1979
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Heart and Circulatory Physiology
- Vol. 236 (1) , H127-H133
- https://doi.org/10.1152/ajpheart.1979.236.1.h127
Abstract
The cardiovascular response to combined stimulation of the aortic nerve (AN) and carotid sinus nerve (CSN) with trains of electrical stimuli was studied in dogs under morphine-chloralose anesthesia. Combined stimulation of both nerves ipsilaterally resulted in systemic arterial depressor responses and cardiac slowing that were 59% and 77% greater (P less than 0.05) than the respective sum of the responses to separate stimulation of these nerves. The depressor response to combined stimulation of these nerves contralaterally was not different (P greater than 0.05) from the sum of the separate responses. However, cardiac slowing to contralateral stimulation of the nerves remained 43% greater (P less than 0.05) than the sum of the individual responses. The results suggest that an interaction between the aortic and carotid baroreceptor reflexes occurs centrally, which causes a greater than additive effect on the autonomic output. The degree of interaction between the reflexes did not change as the delay between the stimulus trains was varied over an interval of 0 and 100 ms. At intervals greater than 100 ms the reflex responses were additive.This publication has 5 references indexed in Scilit:
- Inhibition of the Aortic Depressor Reflex by Continuous Carotid Sinus Nerve StimulationExperimental Biology and Medicine, 1973
- Comparison of the averaged nervous activities of aortic and carotid sinus nervesAmerican Journal of Physiology-Legacy Content, 1967
- Nonlinear Analysis of the Baroreceptor Reflex SystemCirculation Research, 1966
- Summation of bilateral carotid sinus signals in the barostatic reflexAmerican Journal of Physiology-Legacy Content, 1965
- STUDIES ON VAGUS NERVES IN MAN - THEIR ROLE IN RESPIRATORY + CIRCULATORY CONTROL1964