Conservative integration of bacteriophage Mu DNA into pBR322 plasmid.

Abstract
To clarify the 1st step in Mu integrative recombination, a bacterial strain [Escherichia-coli] harboring the plasmid pBR322 was infected and Mu DNA was isolated in a supercoiled form associated with this plasmid. These structures show an association of Mu with pBR322 without any preliminary replication.