MUCORMYCOSIS INFECTION OF THE CRANIOFACIAL STRUCTURES

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Abstract
Mucormycosis is an important, often rapidly fatal, human fungal infection. Infections have been reported in the lungs, kidneys, gastrointestinal tract and head. The typical clinical findings and unusual pathogenesis of the craniofacial form are discussed in this report. This form of mucormycosis, which is being recognized with increasing frequency in uncontrolled diabetics, has a combination of roentgen changes which are probably characteristic: (1) Nodular thickening of the soft tissue lining of many paranasal sinuses, with sparing of the frontal sinuses. (2) Absence of fluid levels in erect roentgenograms. (3) Spotty destruction of the bony walls of multiple paranasal sinuses. Roentgenographic recognition of craniofacial mucormycosis is important because cures have been reported following specific therapy.