Thymidylate synthetase and 2'-deoxyuridylate form a tight complex in the presence of pteroyltriglutamate.
Open Access
- 1 December 1979
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 254 (24) , 12285-12288
- https://doi.org/10.1016/s0021-9258(19)86309-3
Abstract
No abstract availableThis publication has 23 references indexed in Scilit:
- Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanismBiochemistry, 1978
- The effect of raney nickel on the covalent thymidylate synthetase-5-fluoro-2'-deoxyuridylate-5,10-methylenetetrahydrofolate complexBiochemistry, 1976
- Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysisBiochemistry, 1976
- Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.Journal of Clinical Investigation, 1975
- Gel electrophoresis as a means of detecting ternary complex formation of thymidylate synthetaseMicrochemical Journal, 1974
- Fluorinated pyrimidines. Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotidesBiochemistry, 1974
- Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylateBiochemistry, 1974
- Filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrantBiochemistry, 1974
- Thymidylate synthetase: Mechanism of inhibition by 5-fluoro-2′-deoxyuridylateBiochemical and Biophysical Research Communications, 1972
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949