Reverse Transcriptase Activity Associated with R-Type Virus-Like Particles of SV40-Transformed Hamster Cells (TSV5 Clone 2)

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Abstract
A line of hamster cells transformed by SV40 (TSV5 clone 2) contains different DNA polymerase activities. One of them has the same template specificity as viral reverse transcriptases. Partial isolation of R-type virus-like particles from TSV5 clone 2 shows that a reverse transcriptase activity is associated with these RNA viruses. This reverse transcriptase was partially purified and its biochemical properties are described.

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