TREATMENT OF EARLY SYPHILIS WITH PENICILLIN
- 16 March 1946
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 130 (11) , 696-698
- https://doi.org/10.1001/jama.1946.02870110020005
Abstract
Penicillin, properly administered, will cure the majority of patients with primary and secondary syphilis! We base this statement on personal observation of over 900 patients with early syphilis and on intimate knowledge of results obtained by other investigators. Even the most skeptical now are willing to admit the effectiveness of the sodium salts of penicillin injected intramuscularly, usually at a three hour interval day and night, over a period of from seven to ten days. Adequate dosage will produce a percentage of cures in cases of early syphilis (primary and secondary) as good and probably better than chemotherapy. We do not wish to leave the impression that an optimum dosage schedule has been developed. Investigators concerned with this particular subject are still striving toward that goal. However, it is reasonable to suppose that sometime during the next five years such an optimal schedule of treatment for early syphilis will beKeywords
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