Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
Open Access
- 10 August 2010
- journal article
- review article
- Published by Springer Nature in British Journal of Cancer
- Vol. 103 (6) , 759-764
- https://doi.org/10.1038/sj.bjc.6605845
Abstract
Neoadjuvant endocrine therapy has been increasingly employed in clinical practice to improve surgical options for postmenopausal women with bulky hormone receptor-positive breast cancer. Recent studies indicate that tumour response in this setting may predict long-term outcome of patients on adjuvant endocrine therapy, which argues for its broader application in treating hormone receptor-positive disease. From the research perspective, neoadjuvant endocrine therapy provides a unique opportunity for studies of endocrine responsiveness and the development of novel therapeutic agents.Keywords
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