Prevalence of legionellosis among adults: A study of community-acquired pneumonia in France
- 1 September 1987
- journal article
- research article
- Published by Springer Nature in Infection
- Vol. 15 (5) , 328-331
- https://doi.org/10.1007/bf01647732
Abstract
Over a 24-month period, 274 patients with community-acquired pneumonia were hospitalized in Departments of Medicine at hospitals in Bordeaux, Lyon, Marseille, and Toulouse. Etiology of the pneumonia was determined either by organism identification or by indirect immunofluorescence in only 139 cases (51%). The most frequently isolated etiological agents wereStreptococcus pneumoniae (34 cases),Legionella pneumophila (29 cases) andMycoplasma pneumoniae (24 cases). The majority of patients with legionellosis were male (79%), middle aged (mean age: 53 years), and living in urban areas (69%). Their clinical features were atypical and did not differ from those of other pneumonias. Four patients with legionellosis (13.8%) died.L. pneumophila was isolated directly in only three instances. The study confirms the high prevalence of legionellosis (20%) among pneumonias of identified etiology. The fact that these cases had an atypical clinical presentation and that isolation of the organism was difficult reinforce the need to apply the CDC criteria for the interpretation of positive serological titers. In einem Zeitraum von 24 Monaten wurden 274 Patienten mit nosokomialer Pneumonie in internen Abteilungen von Kliniken in Bordeaux, Lyon, Marseille und Toulouse stationär behandelt. Die ätiologische Diagnose der Pneumonie konnte durch Identifizierung des Erregers oder indirekte Immunfluoreszenz nur bei 139 Fällen (51%) gestellt werden. Die häufigsten Erreger warenStreptococcus pneumoniae (34 Fälle),Legionella pneumophila (29 Fälle) undMycoplasma pneumoniae (24 Fälle). Bei den Patienten mit Legionellose waren Männer in der Überzahl (79%), das mittlere Alter betrug 53 Jahre, 69% der Patienten lebten in Städten. Die klinischen Symptome waren uncharakteristisch und unterschieden sich nicht von denen anderer Pneumonien. Vier der an Legionella-Pneumonie erkrankten Patienten verstarben (13,8%).L. pneumophila wurde nur in drei Fällen direkt isoliert. Die vorliegende Untersuchung bestätigt die hohe Prävalenz der Legionellose bei Pneumonien definierter Ätiologie (20%). Die Tatsache, daß diese Fälle ein atypisches klinisches Bild aufwiesen und daß die Erregerisolation schwierig war, bestätigen die Notwendigkeit, positive serologische Befunde nach den CDC-Kriterien zu interpretieren.This publication has 13 references indexed in Scilit:
- Nosocomial Legionnaires' DiseaseJAMA, 1985
- Nosocomial Legionnaires' disease. Epidemiologic demonstration of cooling towers as a sourceJAMA, 1985
- Nosocomial legionellosis, Paris, France. Evidence for transmission by potable waterThe American Journal of Medicine, 1985
- Legionnaires’ DiseaseChest, 1984
- Reactivity of Serum from Patients with Suspected Legionellosis Against 29 Antigens of Legionellaceae and Legionella-Like Organisms by Indirect Immunofluorescence AssayThe Journal of Infectious Diseases, 1983
- Legionnaires' disease: New clinical perspective from a prospective pneumonia studyThe American Journal of Medicine, 1982
- HOSPITAL STUDY OF ADULT COMMUNITY-ACQUIRED PNEUMONIAThe Lancet, 1982
- Maladie des Légionnaires et Leptospiroses : parentés épidémiologiques ou antigéniques ?Medecine Et Maladies Infectieuses, 1980
- False Positive Reactions in the Indirect Fluorescent Antibody Test for Legionnaires' Disease Eliminated by Use of Formolised Yolk-Sac AntigenAnnals of Internal Medicine, 1979
- Legionnaires' DiseaseNew England Journal of Medicine, 1977