Studies in Myasthenia Gravis

Publisher Website
Google Scholar
Abstract
IN an earlier paper, a 30 per cent incidence (77 of 256) of positive staining of striated muscle with the serums of patients with myasthenia gravis was reported.1 An indirect immunofluorescent technic employing a rabbit antihuman 7-S gamma globulin was used. It was observed that of 9 patients whose serums showed positive immunofluorescence before thymectomy, 7 changed to negative after surgery. These changes suggested that positive immunofluorescence, when present, may not be a permanent characteristic finding in the disease.Selected patients were studied in an attempt to establish whether antibody immunofluorescence was a reversible phenomenon that could change not only . . .