Carbapenem and penem antibiotics. III. Synthesis and antibacterial activity of 2-functionalized-methyl penems related to asparenomycins.
- 1 January 1985
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 33 (10) , 4371-4381
- https://doi.org/10.1248/cpb.33.4371
Abstract
Racemic and optically active 2-(heteroaromatic)thiomethyl penems having a 1-(hydroxymethyl)ethylidene or cyclic carbonate side-chain at C-6 (24, 51, 63, 65, 37, 40, 69 and 21b, 61b, 26b, 30b, 64b, 35b, 66b, 39b, 68b) were synthesized, and their antibacterial activities are determined.This publication has 1 reference indexed in Scilit:
- Comparison of in vitro activity of FCE 22101, a new penem, with those of other beta-lactam antibioticsAntimicrobial Agents and Chemotherapy, 1983