The in vivo development of plasma cells
- 1 May 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 27 (5) , 448
- https://doi.org/10.1212/wnl.27.5.448
Abstract
A patient with the clinical diagnosis of meningoencephalitis was studied. The in vivo development of plasma cells in the CNS was demonstrated. All the stages of in vitro mitogen-induced lymphocyte transformation previously described by light microscopy and EM were recapitulated in this analysis of CSF. This apparently represents a local humoral immune reaction in the CNS and provides morphologic support for the concept that the .gamma.-globulin in CSF is produced locally in part, in addition to its origin from the plasma proteins.This publication has 1 reference indexed in Scilit:
- Morphological Studies in the Culture of Human Leucocytes with PhytohaemagglutininBritish Journal of Haematology, 1965