Connective tissue activation
- 1 April 1977
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 20 (3) , 859-868
- https://doi.org/10.1002/art.1780200316
Abstract
This report describes a small basic protein found in human platelets which stimulates hyaluronic acid formation, glucose uptake, and lactate formation in several types of human connective tissue cells. In addition, it stimulates the incorporation of [3H] methyl thymidine into DNA in human synovial cell cultures. This platelet factor (connective tissue activating peptide‐III, CTAP‐III) clearly differs from CTAP‐I, found in human lymphocytes, and may play a role as a mediator of the inflammatory process.This publication has 17 references indexed in Scilit:
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