Die Primärstruktur des Bence-Jones-Proteins Kue Aminosäuresequenz des variablen Abschnitts einer humanen L-Kette vom K-Typ
- 1 January 1979
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 360 (1) , 725-734
- https://doi.org/10.1515/bchm2.1979.360.1.725
Abstract
The complete primary structure of the variable region of Bence-Jones protein Kue was elucitated with the aid of a few tryptic peptides, as well as 1 chymotryptic and 1 BNPS-scatol fragment. As a consequence of the evident homologies to other proteins this protein belongs to subgroup k/I. Protein Kue has some amino acid exchanges in certain positions in common with other proteins, probably giving rise to a new sub-subgroup. The constant region shows no amino acid exchanges in comparison with other human .kappa. L-chains. With Val covering position 191, protein Kue should be grouped per definition as an allotype Km.This publication has 19 references indexed in Scilit:
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