Experience with a commercial preparation of125I-labelled human albumin for study of albumin metabolism
Open Access
- 1 July 1973
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 26 (7) , 499-502
- https://doi.org/10.1136/jcp.26.7.499
Abstract
Evaluation of a commercial preparation of125I-labelled albumin for use in the study of albumin metabolism is described. In eight subjects with normal albumin metabolism the proportion of the dose of radioiodide excreted was stable throughout a period of 17 days, indicating that there was no excessive denaturation of the iodinated albumin. Characteristics of albumin metabolism—pool sizes, catabolic rate, etc—were in agreement with currently accepted normal values. It is concluded that this preparation of iodinated albumin is suitable for metabolic use.Keywords
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