TREATMENT OF CHRONIC POST-TRAUMATIC ORGANIC BRAIN SYNDROME WITH DEXTROAMPHETAMINE

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Abstract
In view of its therapeutic efficacy in the treatment of children with minimal brain dysfunction syndrome, dextroamphetamine was administered to a young adult with a chronic organic brain syndrome secondary to cerebral trauma. That D-amphetamine was critical to the resulting marked diminution in confusion, paranoia and deficit in short-term memory was confirmed by the occurrence of a relapse coincident with placebo administration as part of a doubleblind evaluation. Amitriptyline appeared to potentiate the therapeutic effects of D-amphetamine.

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