Enteropathic Hypoproteinaemia

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Abstract
A child with hypoproteinaemia due to a leakage of protein into the upper small bowel is described. The replacement of dietary protein by amino acids or peptides of low molecular weight was associated with a rise in plasma proteins. An experiment using I131 -tagged human albumin suggests that this effect was produced by diminishing the intestinal leak or protein. The dietetic modifications which we employed lessened the accompanying steatorrhoea. We were unable to show that the harmful effect of dietary protein on the intestine was due to any specific protein.