Labelling of Red Blood Cells in Vitro with Small Amounts of Di-Iso-Propyl-Fluorphosphonate (DF32P)
- 1 January 1968
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 21 (3) , 197-201
- https://doi.org/10.3109/00365516809076985
Abstract
The survival of red blood cells labelled in vitro with radioactive di-iso-propyl-fluorophosphonate (DF32P) was determined in four autotransfusion experiments. The labelling was performed with 0.2 μg of DF32P per ml of red blood cells. The uptake of DF32P was 35–45 %. During the first 24 hours following reinjection of 30–40 ml of the labelled cells the elution of DF32P was 5–10%. After this period, the disappearance, during the period of study (4–7 weeks) was linear at a rate corresponding to a mean life span of 99–125 days.Keywords
This publication has 7 references indexed in Scilit:
- SIMULTANEOUS MEASUREMENT OF SURVIVAL OF 2 POPULATIONS OF ERYTHROCYTES WITH USE OF LABELED DIISOPROPYLFLUOROPHOSPHATE1963
- The Red Cell Chromium Elution Rate in Patients with Some Hematologic DiseasesBlood, 1963
- Analysis of Red‐Cell Survival Curves in Clinical Practice and the Use of Di‐iso‐propylfluorophosphonate (DF32P) as a Label for Red Cells in ManBritish Journal of Haematology, 1962
- FURTHER OBSERVATIONS ON NORMAL SURVIVAL CURVE OF 51CR-LABELLED RED CELLS1961
- The Use of DFP32 as a Red Cell Tag with and without Simultaneous Tagging with Chromium51 in Certain Animals in the Presence or Absence of Random DestructionThe Journal of general physiology, 1960
- LABELING OF RED BLOOD CELLS WITH RADIOACTIVE DIISOPROPYLFLUOROPHOSPHATE (DFP32) - EVIDENCE FOR AN INITIAL RELEASE OF LABEL1960
- The Fate of P32 Labelled Diisopropylfluorophosphonate in the Human Body and Its Use as a Labelling Agent in the Study Of The Turnover of Blood Plasma and Red CellsJournal of Clinical Investigation, 1954