Survival in 1041 patients with consecutive aorto-coronary bypass operations

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Abstract
The first 1041 patients who underwent an isolated aorto-coronary bypass operation in the same institution since it opened in 1971, were followed for up to 10 years to determine their prognosis. The mean follow- up time was 3-5 years. The probability of survival at five years was 94 ±2% (95% confidence limits). This was similar to the survival of the general Dutch population matched for age and sex. Multivariate survival analysis with the proportional hazards model did reveal a relationship of the rate of death with sex and age at operation; however this was not significant. There was a trend to a higher death rate with more vascular involvement (rate ratio of 3 vessel-versus 1 vessel disease of 1-9, N.S.) and a significant association with a low ejection fraction (EF) (ratio EF≤)0.30 v. EF ≥0.55 of 2.7. P<0.05). Though surgery seems to eradicate the poor longterm outlook for patients with more serious vascular disease, the adverse influence of decreased left ventricular function on survival is not changed.