INVESTIGATION OF PORCINE NATURAL-KILLER CELL-ACTIVITY WITH REFERENCE TO AFRICAN SWINE-FEVER VIRUS-INFECTION

  • 1 January 1983
    • journal article
    • research article
    • Vol. 49  (4) , 593-597
Abstract
The natural killing of the human myeloid leukemia cell line by pig mononuclear cells was investigated in an 18 h assay; the most active natural killer (NK) effectors were those cells not adhering to nylon-wool columns or rosetting with sheep red blood cells. Mononuclear cells cultured in the presence of African swine-fever virus maintained NK activity. Pig infected with African swine-fever virus exhibited a suppressed NK activity, possibly due to the sensitivity of NK cells to increased temperatures. The possible role of NK cells in recovery from African swine fever is discussed.