Transgenesis in nonmurine species.
- 1 October 1993
- journal article
- review article
- Published by Wolters Kluwer Health in Hypertension
- Vol. 22 (4) , 630-633
- https://doi.org/10.1161/01.hyp.22.4.630
Abstract
Although the mouse remains the species of choice for most transgenic experimentation, it may be preferable or even necessary to use alternative species for certain applications. We review the strategies by which transgenic technology has been applied to other animals, specifically, the rat, rabbit, pig, sheep, goat, and cow. Additionally, we outline the potential applications of alternative transgenic species with reference to the field of hypertension and cardiovascular research.Keywords
This publication has 22 references indexed in Scilit:
- Secretion of bovine ?-lactalbumin into the milk of transgenic ratsMolecular Reproduction and Development, 1992
- Increased vascular angiotensin formation in female rats harboring the mouse Ren-2 gene.Hypertension, 1992
- Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.Hypertension, 1992
- Transgenic rats carrying the mouse renin gene—Morphological characterization of a low-renin hypertension modelKidney International, 1992
- Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disordersCell, 1990
- Transgenic animals — Production of foreign proteins in milkCurrent Opinion in Biotechnology, 1990
- Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 geneNature, 1990
- Superovulation of Immature Rats by Continuous Infusion of Follicle-Stimulating Hormone1Biology of Reproduction, 1988
- Production of transgenic rabbits, sheep and pigs by microinjectionNature, 1985
- Development of Porcine Ova That Were Centrifuged to Permit Visualization of Pronuclei and Nuclei 1Biology of Reproduction, 1985