Metabolism of Fluorine-Containing Drugs
Top Cited Papers
- 1 April 2001
- journal article
- review article
- Published by Annual Reviews in Annual Review of Pharmacology and Toxicology
- Vol. 41 (1) , 443-470
- https://doi.org/10.1146/annurev.pharmtox.41.1.443
Abstract
This article reviews current knowledge of the metabolism of drugs that contain fluorine. The strategic value of fluorine substitution in drug design is discussed in terms of chemical structure and basic concepts in drug metabolism and drug toxicity.Keywords
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