Variable cytotoxicity of diphtheria toxin 388–granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells

This publication has 38 references indexed in Scilit:

• Acute Myeloid Leukemia
  New England Journal of Medicine, 1999
• Toxicology and Pharmacokinetics of DTGM, a Fusion Toxin Consisting of a Truncated Diphtheria Toxin (DT388) Linked to Human Granulocyte-Macrophage Colony-Stimulating Factor, in Cynomolgus Monkeys
  Toxicology and Applied Pharmacology, 1999
• GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF
  Leukemia, 1998
• Cell-Specific Modulation of Drug Resistance in Acute Myeloid Leukemic Blasts by Diphtheria Fusion Toxin, DT388-GMCSF
  Bioconjugate Chemistry, 1998
• Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
  Nature Medicine, 1997
• Differential expression of granulocyte-macrophage colony-stimulating factor and IL-3 receptor subunits on human CD34+ cells and leukemic cell lines
  Journal of Allergy and Clinical Immunology, 1995
• Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.
  Proceedings of the National Academy of Sciences, 1994
• Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.
  Proceedings of the National Academy of Sciences, 1994
• Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action.
  Journal of Clinical Investigation, 1993
• Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.
  Proceedings of the National Academy of Sciences, 1990