A Convenient Procedure for the Preparation of Alkyl Nitriles from Alkyl Halides. Acetone Cyanohydrin as anIn SituSource of Cyanide Ion
- 1 August 1993
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 23 (16) , 2323-2329
- https://doi.org/10.1080/00397919308013790
Abstract
A convenient preparation of alkyl nitriles from alkyl halides is described. Acetone cyanohydrin is employed as the source of cyanide ion.Keywords
This publication has 11 references indexed in Scilit:
- Regiospecific opening of 1,2-expoxides with acetone cyanohydrin under mildly basic conditionsTetrahedron Letters, 1992
- Acetone Cyanohydrin, a Convenient Formylation Reagent for ArenesSynthetic Communications, 1982
- Umsetzungen von Guanidiniumsalzen mit Alkylbromiden und SäurechloridenEuropean Journal of Organic Chemistry, 1980
- Two-Phase Reactions in Organic ChemistryPublished by Elsevier ,1980
- Synthese von Nitrilen mit TetraalkylammoniumcyanidenEuropean Journal of Organic Chemistry, 1978
- Reactions of Cyanide IonPublished by Springer Nature ,1977
- Photochemistry and radiation chemistry of sulfur-containing amino acids. New reaction of the 1-propenylthiyl radicalsThe Journal of Organic Chemistry, 1975
- Preparation of Nitriles from Halides and Sodium Cyanide. An Advantageous Nucleophilic Displacement in Dimethyl Sulfoxide1aThe Journal of Organic Chemistry, 1960
- Notes- Aliphatic Nitriles from Alkyl ChloridesThe Journal of Organic Chemistry, 1960
- Ueber die Producte der Einwirkung von Cyankalium auf α‐Brompropionsäureester (einfache und bequeme Darstellungsweise der beiden symmetrischen Dimethylbernsteinsäuren)European Journal of Inorganic Chemistry, 1888