The Cancer Research UK experience of pre-clinical toxicology studies to support early clinical trials with novel cancer therapies
- 30 April 2004
- journal article
- review article
- Published by Elsevier in European Journal Of Cancer
- Vol. 40 (6) , 899-906
- https://doi.org/10.1016/j.ejca.2003.12.020
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Hormonal impact of the 17α-hydroxylase/C17,20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancerBritish Journal of Cancer, 2004
- Multi-species toxicology approaches for oncology drugsEuropean Journal Of Cancer, 2004
- Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic ResultsJournal of Clinical Oncology, 2003
- 5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic studyBritish Journal of Cancer, 2003
- A Phase I clinical and pharmacological study of cis-diamminedichloro(2-methylpyridine) platinum II (AMD473)British Journal of Cancer, 2003
- Hepatic Drug Targeting: Phase I Evaluation of Polymer-Bound DoxorubicinJournal of Clinical Oncology, 2002
- Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034British Journal of Cancer, 2001
- Revisions of general guidelines for the preclinical toxicology of new cytotoxic anticancer agents in EuropeEuropean Journal Of Cancer, 1995
- Pharmacokinetics and pharmacodynamics of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione in patients with postmenopausal breast cancerCancer Chemotherapy and Pharmacology, 1991
- General guidelines for the preclinical toxicology of new cytotoxic anticancer agents in Europe : Joint Steering Committee of the European Organization for Research and Treatment of Cancer (EORTC) and the Cancer Research Campaign (CRC)European Journal of Cancer and Clinical Oncology, 1990