Application of Liquid Chromatography/Electrochemistry in Pharmaceutical and Biochemical Analysis: A Critical Review

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Abstract
In the last 20 years, research efforts have increased the number of separation and detection techniques available for the analyses encountered in the development of pharmaceutical compounds. From a holistic point of view, the analytical effort required in the study of a bioactive moiety involves development of analytics to evaluate not just to determine and analyze the compound of interest, but, just as important, the effect the compound has on the biological system into which it is introduced. Therefore, in evaluating an analytical technique such as liquid chromatography/electrochemistry (LCEC) for its applicability to the study of bioactive compounds, it usually becomes apparent that techniques useful to the scientist studying a drug's metabolism are also useful to the scientist studying the physical and chemical properties of the drug.

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