A NEW DANGER IN DINITROPHENOL THERAPY

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Abstract
With the use of alpha-dinitrophenol reaching proportions that must astound and alarm even its enthusiastic advocates, it is felt that this report of another fatality following its administration should be published. REPORT OF CASE A woman, admitted to the Mount Sinai Hospital, May 26, 1934, had an irrelevant past history except for the fact that she had always been obese, averaging 250 pounds (113 Kg.). About one year previously her physician noted moderate hypertension. Two months before admission, after a careful physical examination by her physician, who found only obesity (265 pounds, or 120 Kg.) and hypertension (175 systolic, 100 diastolic), the patient was given sodium alpha-dinitrophenol in doses of one-half grain (0.03 Gm.) three times a day. This dose was gradually increased so that five weeks later the patient was taking 2 grains (0.12 Gm.) three times daily. Her weight at that time was 258 pounds (117 Kg.), a

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